{"id":9082,"date":"2017-04-26T17:59:36","date_gmt":"2017-04-26T21:59:36","guid":{"rendered":"http:\/\/miamiobgyn.co\/?p=9082"},"modified":"2017-04-26T17:59:36","modified_gmt":"2017-04-26T21:59:36","slug":"omega-3s-lower-breast-cancer-risk-obese-women-study-suggests-2","status":"publish","type":"post","link":"https:\/\/www.toplinemd.com\/miami-obgyn\/news\/omega-3s-lower-breast-cancer-risk-obese-women-study-suggests-2\/","title":{"rendered":"Omega-3s could lower breast cancer risk in obese women, study suggests"},"content":{"rendered":"
A new study has suggested that obese women could experience a reduction in the risk of breast cancer through the administration of omega-3 fatty acids.<\/header>\n
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\nOmega-3 fatty acid supplementation was found to reduce breast density in postmenopausal obese women.<\/em><\/div>\n

The study took the form of an open-label, randomized clinical trial of 266 postmenopausal women with high breast density who were either a normal weight, overweight or obese. The findings are published in Cancer Prevention Research<\/em>.<\/p>\n

Dr. Andrea Manni, professor and division chief of endocrinology<\/a>, diabetes<\/a> and metabolism at Penn College of Medicine in Hershey, PA, and colleagues believe that this reduced risk could relate to increased levels of inflammation<\/a> associated with obesity<\/a> leading to breast cancer<\/a>.<\/p>\n

“Omega-3<\/a> fatty acids have an anti-inflammatory effect, so that’s one of the reasons why we suspected it may be particularly effective in obese women,” Dr. Manni says.<\/p>\n

These fatty acids are found in fish oil as well as some plant and nut oils and are believed to convey several health benefits, including reduced risk of coronary heart disease<\/a> and improved cholesterol<\/a> levels.<\/p>\n

Previous studies have suggested that omega-3 fatty acids may help protect against breast cancer in obese women, although results have remained inconclusive. Dr. Manni suspects data obtained from normal-weight women may have caused this inconsistency.<\/p>\n

The aim of the study was to measure the change in the participants’ breast density over 2 years. High breast density appears to be a risk factor for breast cancer; according to the National Cancer Institute (NCI), women with dense breast have a four- to sixfold increased risk of developing the disease.<\/p>\n

“The higher the breast density, the more likely the woman will develop breast cancer,” asserts Dr. Manni.<\/p>\n

However, scientists are divided as to why breast density is an independent cancer<\/a> risk.<\/p>\n

Reduction in breast density only observed in obese participants<\/h2>\n

All the participants had a high breast density (of 25% or greater) at the outset of the study, detected via routine screening mammograms.<\/p>\n

Participants were randomized into five different treatment groups. Two groups received differing dosages of the anti-estrogen drug Raloxifene (60 mg and 30 mg), one group received the prescription omega-3 drug Lovaza (4 gm) and one group received 30 mg of Raloxifene combined with 4 gm of Lovaza. A control group received no treatment.<\/p>\n

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Fast facts about fish oils<\/span><\/p>\n