{"id":1431,"date":"2023-01-18T13:36:07","date_gmt":"2023-01-18T13:36:07","guid":{"rendered":"https:\/\/www.toplinemd.com\/omar-rashid\/?p=1431"},"modified":"2026-02-25T15:27:50","modified_gmt":"2026-02-25T15:27:50","slug":"do-alcohol-tobacco-increase-the-risk-of-neuroendocrine-tumors-of-the-small-intestine","status":"publish","type":"post","link":"https:\/\/www.toplinemd.com\/omar-rashid\/do-alcohol-tobacco-increase-the-risk-of-neuroendocrine-tumors-of-the-small-intestine\/","title":{"rendered":"Does Alcohol &#038; Tobacco Increase the Risk of Neuroendocrine Tumors | Medicus Elite"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">First off, to better understand whether smoking tobacco and alcohol consumption increases the risk of cancer or neuroendocrine tumors in the small intestine, we must better understand these tumors and the effects of these compounds on the body and bodily cells altogether.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Neuroendocrine tumors are rare malignancies that develop in the neuroendocrine system&#8217;s cells. NET cancers are rare, and earlier, they were often overlooked. However, with the advancements in cancer testing and diagnostic methods, experts can discover these diseases faster and offer faster and more effective neuroendocrine tumor treatment earlier.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In this article, <\/span><a href=\"\/omar-rashid\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Dr. Omar Rashid<\/span><\/a><span style=\"font-weight: 400;\"> and his expert team will discuss the nature of these malignancies and try to shed more light on whether alcohol and tobacco use increases the risk of these cancers.<\/span><\/p>\n<h2><b>What Are NETs or Neuroendocrine Tumors?\u00a0<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">As stated above, these are uncommon diseases that develop in the cells of the neuroendocrine system. The cells share traits of hormone-producing cells and nerve cells, linking the endocrine system to the nervous system, and they are scattered throughout the human body.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">There are several types of these tumors, and many show symptoms similar to other, often less severe medical conditions.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Once considered especially rare, nowadays, diseases are being diagnosed in more and more patients, not necessarily because of the rising NET rates but because of improved diagnostics, which also increases the successful outcome of neuroendocrine tumor treatment.<\/span><\/p>\n<h2><b>Types of Neuroendocrine Tumors<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Typically, these malignancies are classified as either primary or secondary, with the first being cancers that haven&#8217;t spread yet. Secondary tumors are those that have managed to metastasize, usually to the nearest lymph nodes, liver, or bones.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">These tumors may also be classified based on their location. Here are the most common tumor types regarding the location of occurrence:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\"><b>GI or gastrointestinal tract: <\/b><span style=\"font-weight: 400;\">They are most common in the large intestine, small intestine, and appendix.<\/span><\/li>\n<li style=\"font-weight: 400;\"><b>Lung: <\/b><span style=\"font-weight: 400;\">This organ is the second most common place where these tumors may develop. Around 30% of NETs develop in the bronchial system.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\"><b>Pancreas: <\/b><span style=\"font-weight: 400;\">Around 7% of these tumors develop here. They were previously called islet tumors.\u00a0<\/span><\/li>\n<\/ul>\n<h2><b>Symptoms<\/b><\/h2>\n<p><img decoding=\"async\" class=\"aligncenter size-full wp-image-1433\" src=\"https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/02\/Symptoms-2.jpg\" alt=\"Unknown Woman-doctor and Female Patient Sitting and Talking at Medical Examination in Sunny Clinic, Close-up.\" width=\"1000\" height=\"667\" srcset=\"https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/02\/Symptoms-2-200x133.jpg 200w, https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/02\/Symptoms-2-300x200.jpg 300w, https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/02\/Symptoms-2-400x267.jpg 400w, https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/02\/Symptoms-2-600x400.jpg 600w, https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/02\/Symptoms-2-768x512.jpg 768w, https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/02\/Symptoms-2-800x534.jpg 800w, https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/02\/Symptoms-2.jpg 1000w\" sizes=\"(max-width: 1000px) 100vw, 1000px\" \/><\/p>\n<p><span style=\"font-weight: 400;\">The signs of neuroendocrine tumors will usually vary depending on their location. On that end, carcinoid syndrome is often the most prevalent group of symptoms that patients produce.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Carcinoid syndrome occurs when the tumors affect normal hormone production. Only around 10% of patients with these conditions develop the syndrome, and the most common symptoms may include the following:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Head and neck flushing<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Diarrhea and cramps in the abdomen<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Gassiness<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Edema<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Wheezing<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Decreased libido and erectile dysfunction<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Jaundice<\/span><\/li>\n<\/ul>\n<h2><b>The Causes Behind Neuroendocrine Tumors<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Whether they develop in the lungs or the small intestine, researchers aren&#8217;t exactly sure what triggers these cell mutations. However, the medical community has linked these diseases to a few inherited syndromes, such as:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\"><b>MEN1, or multiple endocrine neoplasia type 1<\/b><span style=\"font-weight: 400;\">, which causes the adrenal thyroid, and parathyroid glands to form tumors or become overactive.<\/span><\/li>\n<li style=\"font-weight: 400;\"><b>MEN2, or multiple endocrine neoplasia type 2<\/b><span style=\"font-weight: 400;\">, which affects the pancreas, parathyroid, or pituitary gland to become overactive or form tumors.<\/span><\/li>\n<li style=\"font-weight: 400;\"><b>Tuberous sclerosis complex,<\/b><span style=\"font-weight: 400;\"> with symptoms such as autism, skin birthmarks, and developmental delay in early childhood.<\/span><\/li>\n<li style=\"font-weight: 400;\"><b>Von-Hippel-Lindau syndrome,<\/b><span style=\"font-weight: 400;\"> in which tumors may develop in various areas of the body.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\"><b>Neurofibromatosis type1,<\/b><span style=\"font-weight: 400;\"> in which tumors grow on the nerves and the skin.<\/span><\/li>\n<\/ul>\n<h2><b>Do Smoking Tobacco and Drinking Alcohol Increase the Risk of NETs?\u00a0<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">As of now, researchers aren&#8217;t exactly sure whether these two compounds can directly trigger the development of these malignancies. According to state-wide scientific <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6961822\/\" target=\"_blank\" rel=\"nofollow noopener\"><span style=\"font-weight: 400;\">research conducted in Utah<\/span><\/a><span style=\"font-weight: 400;\"> between 1996 and 2014, smoking tobacco and alcohol use may be risk factors for neuroendocrine tumors of the small intestine, independent of family history. Still, when looking at the findings overall, experts stated that other yet-to-defined exposures might be more prevalent risk factors. On that end, the scientific consensus is that tobacco and alcohol present a modest risk of cancer when it comes to small intestine NET, specifically.\u00a0<\/span><\/p>\n<h2><b>More About the Effects of Alcohol and Tobacco\u00a0<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">The scientific community strongly agrees that alcohol consumption can contribute to the development of several malignancies.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">According to evidence, the more a person drinks, over time, regularly, the higher the chances of developing an alcohol-related malignancy.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Clear patterns show that prolonged and regular alcohol consumption may lead to the development of the following cancers:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Head and neck tumors<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Colorectal cancer<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Esophageal cancer<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Liver cancer<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Breast cancer<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Apart from that, current research results suggest that alcohol consumption may increase the risks of other cancers, such as pancreatic, prostate, kideny cancers, and melanoma.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Tobacco, on the other hand, may increase cancer risk almost everywhere in the body. Even though lung cancer comes first to mind, in reality, smoking can increase malignancy development almost everywhere in the body, including the following:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Cervix<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Throat and mouth<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Stomach<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Larynx<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Bladder<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Rectum and colon<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Esophagus<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Renal pelvis and kidney<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Liver<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Lungs<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Bronchi<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Trachea<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Blood (in the form of acute myeloid leukemia)<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Esophagus<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Pancreas<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Just like in the case of alcohol, quitting can reduce the risk of cancer development. However, both of them may be hard to stop because of their addictive characteristics. Fortunately, several organizations and programs aim to help kick these unhealthy habits.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Lastly, epidemiologic research suggests that individuals who use both substances are at a higher risk of developing oral, throat, and esophagus cancers than those who either drink or smoke. While doing only one of these can somewhat lower the risks, individuals should consider quitting both to help decrease the risk of medical issues in general.\u00a0<\/span><\/p>\n<h2><b>How Are NETs Diagnosed?<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Now that we&#8217;ve established the possible links between neuroendocrine tumors and alcohol and tobacco use, we should highlight the most prevalent methods to diagnose these tumors.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The typical tests may include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Biopsy<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Urinalysis<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Coren needle biopsy<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">CT scans<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">MRI scans<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Biochemical tests<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">PET scans<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">During the diagnostic process, healthcare experts will also grade the tumors to create an effective treatment plan.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Doctors usually grade these tumors in the following way:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\"><b>Grade 1 <\/b><span style=\"font-weight: 400;\">is a low-grade tumor where the cells multiply slowly, and cancer grows slowly.<\/span><\/li>\n<li style=\"font-weight: 400;\"><b>Grade 2 <\/b><span style=\"font-weight: 400;\">is an intermediate-grade tumor where the cells divide faster.<\/span><\/li>\n<li style=\"font-weight: 400;\"><b>Grade 3<\/b><span style=\"font-weight: 400;\"> tumors grow quickly, and the patient needs swift medical assistance.\u00a0<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Experts may also classify and evaluate the tumors by the degree of differentiation.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In the case of well-differentiated tumors, the cells look very similar to healthy cells. On the other hand, in poorly-differentiated NETs, the cells resemble typical cancerous cells more.\u00a0<\/span><\/p>\n<h2><b>Treating Neuroendocrine Tumors<\/b><\/h2>\n<p><img decoding=\"async\" class=\"aligncenter size-full wp-image-1434\" src=\"https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/02\/Treating-Neuroendocrine-Tumors.jpg\" alt=\"Shot of a Doctor Showing a Patient Some Information on a Digital Tablet\" width=\"1000\" height=\"563\" srcset=\"https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/02\/Treating-Neuroendocrine-Tumors-200x113.jpg 200w, https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/02\/Treating-Neuroendocrine-Tumors-300x169.jpg 300w, https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/02\/Treating-Neuroendocrine-Tumors-400x225.jpg 400w, https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/02\/Treating-Neuroendocrine-Tumors-600x338.jpg 600w, https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/02\/Treating-Neuroendocrine-Tumors-768x432.jpg 768w, https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/02\/Treating-Neuroendocrine-Tumors-800x450.jpg 800w, https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/02\/Treating-Neuroendocrine-Tumors.jpg 1000w\" sizes=\"(max-width: 1000px) 100vw, 1000px\" \/><\/p>\n<p><span style=\"font-weight: 400;\">Typically, these malignancies are treated with surgery, but if the cancer is large or has spread, experts may also opt for:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Chemotherapy as it uses different drugs to kill malignant cells.<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Somatostatin analogs inhibit excess hormone production, which may slow down tumor growth.<\/span><\/li>\n<li style=\"font-weight: 400;\"><span style=\"font-weight: 400;\">Targeted therapy uses drugs that target specific proteins and genes to eliminate cancer cells.\u00a0<\/span><\/li>\n<\/ul>\n<h2><b>Learn More<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Knowing the most prominent cancer risk and cancer-causing substances can help you quit harmful habits and promote healthy lifestyle changes, which can minimize the chances of disease. If you&#8217;d like to learn more about the possible links between alcohol, tobacco, and small intestine neuroendocrine tumors, feel free to schedule an appointment with Dr. Rashid. <\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>First off, to better understand whether smoking tobacco and alcohol consumption increases the risk of cancer or neuroendocrine tumors in<\/p>\n","protected":false},"author":3,"featured_media":1432,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[151],"tags":[156,152,154,153,155],"class_list":["post-1431","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-small-intestine","tag-neuroendocrine-tumor-treatment","tag-neuroendocrine-tumors","tag-risk-of-cancer","tag-small-intestine","tag-smoking-tobacco"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.0.1 - aioseo.com -->\n\t<meta name=\"description\" content=\"What are neuroendocrine tumors, and does smoking tobacco increase the risk of neuroendocrine cancer of the small intestine? 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