{"id":1491,"date":"2023-07-10T08:48:42","date_gmt":"2023-07-10T08:48:42","guid":{"rendered":"https:\/\/www.toplinemd.com\/omar-rashid\/?p=1491"},"modified":"2023-07-10T08:48:42","modified_gmt":"2023-07-10T08:48:42","slug":"cholangitis-causes-symptoms-and-treatments","status":"publish","type":"post","link":"https:\/\/www.toplinemd.com\/omar-rashid\/cholangitis-causes-symptoms-and-treatments\/","title":{"rendered":"Cholangitis: Causes, Symptoms, and Treatments"},"content":{"rendered":"<h2><b>What Is Cholangitis?\u00a0<\/b><\/h2>\n<p><span style=\"font-weight: 400\">Cholangitis can be best described as a condition in which the bile duct becomes swollen or inflamed. According to the American Liver Foundation, the condition can be categorized as a liver disease type which can be broken into several subcategories:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">PBC or primary biliary cholangitis<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">PSC or primary sclerosing cholangitis<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Secondary cholangitis<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Immune cholangitis<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">In this article, <\/span><a href=\"https:\/\/www.toplinemd.com\/omar-rashid\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400\">Dr. Omar Rashid<\/span><\/a><span style=\"font-weight: 400\"> and his expert team will discuss the main characteristics of bile duct inflammation, address the causes of cholangitis, its most prominent symptoms, and available treatment options.\u00a0<\/span><\/p>\n<h2><b>The Role of The Bile Duct<\/b><\/h2>\n<p><span style=\"font-weight: 400\">The bile duct is responsible for carrying bile from the gallbladder and the liver to the small intestine. The bile is a yellowish-brown or green fluid that aids in digesting and absorbing fats. Also, it aids in clearing liver waste.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">When these ducts get blocked or inflamed, the bile fluid can get back to the liver, leading to complications such as bile damage. Still, some types of cholangitis are only very mild, while others can even be life-threatening.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">In this respect, experts differentiate two types of cholangitis:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Chronic develops slowly over a more extended period, causing milder symptoms over months\/years.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Acute, which happens suddenly, causing symptoms abruptly.<\/span><\/li>\n<\/ul>\n<p><img decoding=\"async\" class=\"aligncenter size-full wp-image-1493\" src=\"https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/07\/The-Role-of-The-Bile-Duct.jpg\" alt=\"Diagnosis Cholangitis Written in the Diagnostic Form and Pills\" width=\"1000\" height=\"667\" srcset=\"https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/07\/The-Role-of-The-Bile-Duct-200x133.jpg 200w, https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/07\/The-Role-of-The-Bile-Duct-300x200.jpg 300w, https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/07\/The-Role-of-The-Bile-Duct-400x267.jpg 400w, https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/07\/The-Role-of-The-Bile-Duct-600x400.jpg 600w, https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/07\/The-Role-of-The-Bile-Duct-768x512.jpg 768w, https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/07\/The-Role-of-The-Bile-Duct-800x534.jpg 800w, https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/07\/The-Role-of-The-Bile-Duct.jpg 1000w\" sizes=\"(max-width: 1000px) 100vw, 1000px\" \/><\/p>\n<h2><b>Cholangitis Symptoms<\/b><\/h2>\n<p><span style=\"font-weight: 400\">Typically, the cholangitis symptoms the patient experience will depend on the type of condition they have and for how long. That said, every patient with cholangitis may experience slightly different cholangitis symptoms. Still, many of them will probably have the following:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Dry eyes<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Itchy skin<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Fatigue<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Dry mouth<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">In the case of chronic bile duct inflammation, the most prominent cholangitis symptoms usually are the following:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Pain in the upper ride side of your body<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Swollen ankles and feet<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Night sweats<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Muscle pain<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Hyperpigmentation<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Joint or bone pain<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Water retention<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Xanthomas or fat deposits around the body, such as, under the eyelids, eyes, knees, elbows, soles of the feet, and palms<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Greasy bowel movements or diarrhea, often clay-colored<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Weight loss<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Memory problems and mood changes<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">Acute cholangitis may often trigger different symptoms, which may include the following:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Back pain<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Nausea<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Chills<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Vomiting<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Dark urine<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">High fever lasting longer than a day<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Abdominal cramps or pain on the abdomen\u2019s upper right side<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Jaundice<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Confusion<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Low blood pressure<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">In dom cases, cholangitis symptoms may also include the following:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">High cholesterol<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Enlarged or swollen spleen<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Swollen or enlarged liver<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Brittle and weak bones<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Underactive thyroid<\/span><\/li>\n<\/ul>\n<h2><b>The Causes of Cholangitis<\/b><\/h2>\n<p><span style=\"font-weight: 400\">There can be several that can lead to the development of the condition, while in other cases, experts can\u2019t pinpoint the exact thing that leads to cholangitis.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">In most cases, experts agree that chronic cholangitis may be a form of autoimmune disease, which means that the body is mistakenly attacking its own bile ducts, leading to swelling.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">As the problem lingers, the inflammation may lead to liver tissue scarring and hard tissue growth within the ducts. Scarring can create a blockage or make the ducts narrow and hard.<\/span><\/p>\n<p><span style=\"font-weight: 400\">On the other hand, the acute causes of cholangitis are often the following:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Gallstones<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Tumor<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Blockages<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Bacterial infections<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">Sometimes, bile duct inflammation can develop due to environmental causes:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Smoking<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Being exposed to infections<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Being exposed to chemicals<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">There are also risk factors that can increase the chances of developing the condition. These are:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Genetics: Cholangitis may have a hereditary component to it<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Age: It\u2019s most common between the <\/span><a href=\"https:\/\/www.niddk.nih.gov\/health-information\/liver-disease\/primary-sclerosing-cholangitis\/definition-facts\" target=\"_blank\" rel=\"nofollow noopener\"><span style=\"font-weight: 400\">ages of 30 and 50<\/span><\/a><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Gender: PSC is more prevalent in men, while PBC is in women.<\/span><\/li>\n<\/ul>\n<h2><b>Diagnosing Cholangitis<\/b><\/h2>\n<p><span style=\"font-weight: 400\">Fortunately, experts can diagnose cholangitis in various ways via several scans and tests. On that note, your healthcare provider may recommend one or some of the following tests if they suspect you might have cholangitis:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Liver function tests<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">CBC or complete blood count<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Cholesterol test<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Blood culture test<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Anti-mitochondrial antibody test<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">Several imaging test types are available to enable doctors to see how the ducts and the liver function. Even though these tests aren\u2019t always necessarily needed, they can aid the doctor in confirming a more precise diagnosis and rule out other diseases which may produce similar or the same symptoms. These tests may include the following:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Ultrasound<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">MRI scans<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">CT scans<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">ERCP or endoscopic retrograde cholangiopancreatography<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">PTC percutaneous transhepatic cholangiography<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">Apart from all this, patients may be recommended to give stool, urine, or bile samples.\u00a0<\/span><\/p>\n<h2><b>Cholangitis Treatment<\/b><\/h2>\n<p><span style=\"font-weight: 400\">There are usually different treatment plans to address acute and chronic cholangitis, mostly based on the things that cause the problem. Cholangitis treatment will also depend on when the patient receives the diagnosis. Both of these conditions can lead to severe complications if left unaddressed.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">Early treatment is extremely pivotal for making a swift and complete recovery. For that, providers may recommend penicillin, metronidazole, ceftriaxone, ciprofloxacin, or other antibiotics for at least up to ten days.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">On the other hand, they may also recommend the following procedures:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Bile duct drainage<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">IV fluids<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">Unfortunately, chronic cholangitis will often not respond to medications. Still, a compound called ursodeoxycholic acid may help with protecting the liver, but it won\u2019t be able to help with cholangitis.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">For chronic cholangitis, treatment options will often include the following:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Symptom management<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Liver function monitoring<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Several procedures that can open blocked bile ducts<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">Procedures for both acute and chronic cases are:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Percutaneous therapy<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Endoscopic therapy<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Liver transplant<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Surgery<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400\">On the other hand, patients may also need treatment to manage the side effects of the disease, such as digestion problems, bone weakness, and hypertension.<\/span><\/p>\n<h2><b>Cholangitis Complications<\/b><\/h2>\n<p><span style=\"font-weight: 400\">If left untreated, cholangitis can lead to serious health issues, such as:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400\"><b>Gallstones:<\/b><span style=\"font-weight: 400\"> The blocked bile duct may harden into stones, leading to infections and pain.<\/span><\/li>\n<li style=\"font-weight: 400\"><b>Enlarged spleen<\/b><span style=\"font-weight: 400\">: When liver function is impaired, it can\u2019t filter out toxins and waste, and old blood cells may collect in the spleen, causing swelling.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><b>Liver problems:<\/b><span style=\"font-weight: 400\"> Untreated cholangitis can cause cirrhosis, slowing down liver function, and may even cause total liver failure. It may also increase the risks associated with liver cancer.<\/span><\/li>\n<li style=\"font-weight: 400\"><b>Blood infection:<\/b><span style=\"font-weight: 400\"> Acute cholangitis may cause sepsis, which can do massive damage to the body and may even be lethal if not addressed in time.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><b>Enlarged veins: <\/b><span style=\"font-weight: 400\">The liver\u2019s high blood pressure may cause unnecessary pressure to the veins in the stomach, leading to inflammation and broken veins.\u00a0<\/span><\/li>\n<\/ul>\n<p><img decoding=\"async\" class=\"aligncenter size-full wp-image-1494\" src=\"https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/07\/Cholangitis-Complications.jpg\" alt=\"Legs Pain Concept - Legs Tied With Rope Isolated on White\" width=\"1000\" height=\"667\" srcset=\"https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/07\/Cholangitis-Complications-200x133.jpg 200w, https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/07\/Cholangitis-Complications-300x200.jpg 300w, https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/07\/Cholangitis-Complications-400x267.jpg 400w, https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/07\/Cholangitis-Complications-600x400.jpg 600w, https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/07\/Cholangitis-Complications-768x512.jpg 768w, https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/07\/Cholangitis-Complications-800x534.jpg 800w, https:\/\/www.toplinemd.com\/omar-rashid\/wp-content\/uploads\/sites\/132\/2023\/07\/Cholangitis-Complications.jpg 1000w\" sizes=\"(max-width: 1000px) 100vw, 1000px\" \/><\/p>\n<h2><b>Timely Diagnosis and Treatment Are Crucial\u00a0<\/b><\/h2>\n<p><span style=\"font-weight: 400\">As mentioned, the symptoms will be a bit different for each patient, sometimes even going unnoticed. Still, an early diagnosis and treatment will always give a more successful outcome, which will also keep the complications from developing or progressing.\u00a0\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">That said, people should watch out for telltale signs and should attend regular checkups and screenings to ensure everything\u2019s fine.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">And if you do have cholangitis, receiving immediate and expert treatment is your best chance for making a full recovery or for easing your symptoms. On that note, feel free to reach out to our practice to learn more about the nature of the condition and gain more insight into the characteristics of the treatment options available.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>What Is Cholangitis?\u00a0 Cholangitis can be best described as a condition in which the bile duct becomes swollen or inflamed.<\/p>\n","protected":false},"author":3,"featured_media":1492,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[209,181],"tags":[213,211,210,212,214],"class_list":["post-1491","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cholangitis","category-liver","tag-bile-duct-inflammation","tag-causes-of-cholangitis","tag-cholangitis-symptoms","tag-cholangitis-treatment","tag-what-is-cholangitis"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.toplinemd.com\/omar-rashid\/wp-json\/wp\/v2\/posts\/1491","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.toplinemd.com\/omar-rashid\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.toplinemd.com\/omar-rashid\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.toplinemd.com\/omar-rashid\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.toplinemd.com\/omar-rashid\/wp-json\/wp\/v2\/comments?post=1491"}],"version-history":[{"count":0,"href":"https:\/\/www.toplinemd.com\/omar-rashid\/wp-json\/wp\/v2\/posts\/1491\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.toplinemd.com\/omar-rashid\/wp-json\/wp\/v2\/media\/1492"}],"wp:attachment":[{"href":"https:\/\/www.toplinemd.com\/omar-rashid\/wp-json\/wp\/v2\/media?parent=1491"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.toplinemd.com\/omar-rashid\/wp-json\/wp\/v2\/categories?post=1491"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.toplinemd.com\/omar-rashid\/wp-json\/wp\/v2\/tags?post=1491"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}