Hypoactive sexual desire disorder (HSDD) is the medical term for decreased libido. It is one of the most common forms of sexual dysfunction in women. It is defined as the deficiency or absence of sexual fantasies and desire for sexual activity which leads to distress, frustration or inter-relationship difficulties. Many factors play into adult female sexual desire including relationship status, self-esteem, stress, menstrual cycles, hormonal contraceptives, other medications, hysterectomy, perimenopause and menopausal states. The diagnosis of HSDD is made by answering a questionnaire called the Decreased Sexual Desire Screener. HSDD can negatively impact a woman’s quality of life, but treatment is available.